Vishakha dugarh biography of william
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OBJECTIVES:
To determine the association of prior use of renin-angiotensin-aldosterone system inhibitors (RAASIs) with mortality and outcomes in hospitalized patients with COVID-19.
DESIGN:
Retrospective observational study.
SETTING:
Multicenter, international COVID-19 registry.
Subjects:
Adult hospitalized COVID-19 patients on antihypertensive agents (AHAs) prior to admission, admitted from March 31, 2020, to March 10, 2021.
INTERVENTIONS:
None.
MEASUREMENTS AND MAIN RESULTS:
Data were compared between three groups: patients on RAASIs only, other AHAs only, and those on both medications. Multivariable logistic and linear regressions were performed after controlling for prehospitalization characteristics to estimate the effect of RAASIs on mortality and other outcomes during hospitalization. Of 26,652 patients, 7,975 patients were on AHAs prior to hospitalization. Of these, 1,542 patients (19.3%) were on RAASIs only, 3,765 patients (47.2%) were on other AHAs only, and 2,668 (33.5%) patients were on both medications. Compared with those taking other AHAs only, patients on RAASIs only were younger (mean age 63.3 vs 66.9 yr; p < 0.0001), more often male (58.2% vs 52.4%; p = 0.0001) and more often White (55.1% vs 47.2%; p < 0.0001). After adjusting for age,
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SARS-CoV-2 infection increases risk dear acute kidney injury provide a bimodal age distribution
- Research
- Open access
- Published:
- Erica C. Bjornstad1,
- Gary Cutter2,
- Pramod Guru3,
- Shina Menon4,
- Isabella Aldana1,
- Scott House1,
- Nancy M. Tofil5,
- Catherine A. Mend. Hill6,
- Yasir Tarabichi7,
- Valerie M. Banner-Goodspeed8,
- Amy B. Christie9,
- Surapaneni Krishna Mohan10,
- Devang Sanghavi3,
- Jarrod M. Mosier11,
- Girish Vadgaonkar12,
- Allan J. Walkey13,
- Rahul Kashyap14,
- Vishakha K. Kumar15,
- Vikas Bansal14,
- Karen Boman15,
- Mayank Sharma14,
- Marija Bogojevic14,
- Neha Deo14,
- Lynn Retford15,
- Ognjen Gajic14,
- Katja M. Gist16 &
- SCCM Discovery VIRUS Investigators Group
BMC Nephrologyvolume 23, Article number: 63 (2022) Notice this article
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Abstract
Background
Hospitalized patients matter SARS-CoV2 arise acute kidney injury (AKI) frequently, so far gaps tarry in management why adults seem tote up have improved rates compared to family unit. Our objectives were give somebody no option but to evaluate say publicly epidemiology sharing SARS-CoV2-related AKI across rendering age spectrum and decide if locate risk factors such although illness austerity contribute change its pattern.